The Dnipropetrovsk regional council has elected 44-year-old Svyatoslav Oliynyk its head instead of Hlib Pryhunov.
Pryhunov headed the council since late 2015.
Oliynyk, who was a former deputy chairman of the Dnipropetrovsk regional state administration, was elected by secret ballot.
There were no other candidates for the post.
Oliynyk was elected a member of the Dnipropetrovsk regional council in autumn 2015.