Foreign Minister Pavlo Klimkin has tendered his resignation. He announced this in a video post on Facebook.
"I think this is a right thing to do in human terms, in terms of normal political culture because, after all, we need it. I have informed the newly-appointed president of Ukraine accordingly," he said.
He said "a part of our foreign policy success is honest and sincere unlike domestic policy".
He said he would run for parliament.
He said he would send his resignation letter to parliament and President-elect Volodymyr Zelensky when he takes office on 20 May.